N-terminal Pro B-type Natriuretic Peptide (NT-proBNP) Assay Kit (Magnetic Particle Chemiluminescence)

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Biochip Langdao (Tianjin)Medical Technology Limited

Business Type:Manufacturer


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Product Information

  • Model:30tests/kit 60tests/kit
  • Certification:CE
  • Net Weight:1kg
  • Trademark:WELL-FIT
  • Place of Origin:China
  • Warranty:1 year


1.Product Overview

 [product name] : N terminal brain natriuretic peptide precursor (NT - proBNP)

 [Package Specification] : 30 tests/kit;60 tests/kit

 [Applicable Device] : CLite-160i

 [Specimen Type] : plasma

 [Storage] : 2-8℃

 [Product validity] : 12 months

 [Detection method] : magnetic particle chemiluminescence method


2.technique principle

Double antibody sandwich method was used in the kit. The detection principle is: the sample to be tested, R1 reagent, R2 reagent and M reagent are mixed for incubation, and the fluorescein (FITC) labeled NT - proBNP antibody 1 in R1 reagent and the alkaline phosphatase (ALP) labeled NT - proBNP antibody 2 in R2 reagent are combined with the NT - proBNP antigen molecules in the sample to form an immune complex. The immune complex is further captured by anti-FITC antibodies coupled to the surface of the magnetic particle and adsorbed to the surface of the magnetic particle. After washing, the unbound material was removed and the luminescent substrate was added, ALP catalyzed the luminescence of the substrate, and the relative luminescence intensity (RLU) was determined.


3.Clinical significance

Nterminal brain natriuretic peptide precursor, as a effective marker of heart failure, can independently predict increased ventricular pressure condition, for congestive heart failure and its complications caused by breathing difficulties, primary hypertension and its associated with left ventricular dysfunction and other cardiovascular diseases the auxiliary diagnosis and treatment of evaluation monitoring is of important value.

4.Product features and indicators

High sensitivity: the detection limit is not higher than 30ng/L;

Wide linear range: the sample in the range of [30,32000](ng/L) without dilution;

Good correlation: correlation R > 0.95 with ROCHE reagent;

Good stability: the calibration cycle can be up to 14 days, the reagent can be stored at 4℃ for 1 year;

Fast results: only 16-18 minutes to get results.

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